What is Brugada Syndrome?

Brugada syndrome is a rare genetic disorder that affects the heart’s electrical system and can lead to a dangerous irregular heart rhythm called ventricular fibrillation (cardiac arrest). Many people with Brugada syndrome don’t show noticeable symptoms and are unaware that they have it until they have a serious cardiac event.

In this article, you will learn more about:

  • How is Brugada Syndrome Diagnosed?  
  • Risk Factors
  • Causes of Brugada Syndrome
  • Symptoms of Brugada Syndrome
  • Treatments for Brugada Syndrome
  • Additional Resources
Download or view our patient education handout on Brugada Syndrome.

How is Brugada Syndrome Diagnosed? 

Dr. Yoo will use a combination of a physical exam, medical history, and testing, such as an electrocardiogram (EKG/ECG) to look for what’s called a Brugada sign. 

If you have this sign but don’t show symptoms, Dr. Yoo may also perform an electrophysiology (EP) study

In addition, Dr. Yoo may recommend genetic screening using Invitae.

Risk Factors include:

  • family history
  • being male Asian heritage
  • fever and respiratory illnesses which can trigger symptoms

Causes of Brugada Syndrome include:

  • structural heart abnormality
  • electrolyte imbalance
  • certain medications

Symptoms of Brugada Syndrome

Most people with Brugada don’t experience or notice symptoms unless they have a cardiac event. Those who do experience symptoms may experience:

  • fainting (syncope)
  • irregular, rapid, or fluttering
    heartbeat (palpitations)
  • sudden cardiac arrest (SCA)
  • gasping or labored breathing, especially at night
  • fast and chaotic heartbeat
  • seizures

Treatments for Brugada Syndrome

Treatment depends on your level of risk; if you are at high risk, treatment may include an implantable cardioverter- defibrillator (ICD), drug therapy, and catheter ablation. However, you can also reduce risks of abnormal rhythms with the following lifestyle modifications:

  • treating fever and respiratory illnesses aggressively
  • avoiding certain heart medications and stimulants
  • limiting alcohol
  • avoiding high stress activities